- Beckmann, K, Santaolalla, A, Helleman, J, Carroll, P, Ha Chung, B, Shiong Lee, L et al.. Comparison of Characteristics, Follow-up and Outcomes of Active Surveillance for Prostate Cancer According to Ethnicity in the GAP3 Global Consortium Database. Eur Urol Open Sci. 2021;34 :47-54. doi: 10.1016/j.euros.2021.09.012. PubMed PMID:34934967 PubMed Central PMC8655390.
- Godtman, RA, Remmers, S, Aus, G, Nelen, V, van Eycken, L, Villers, A et al.. Intervention-related Deaths in the European Randomized Study of Screening for Prostate Cancer. Eur Urol Open Sci. 2021;34 :27-32. doi: 10.1016/j.euros.2021.09.014. PubMed PMID:34934964 PubMed Central PMC8655382.
- Bespalov, A, Barchuk, A, Auvinen, A, Nevalainen, J. Cancer screening simulation models: a state of the art review. BMC Med Inform Decis Mak. 2021;21 (1):359. doi: 10.1186/s12911-021-01713-5. PubMed PMID:34930233 PubMed Central PMC8690438.
- Eskelinen, T, Veitonmäki, T, Kotsar, A, Tammela, TLJ, Pöyhönen, A, Murtola, TJ et al.. Improved renal cancer prognosis among users of drugs targeting renin-angiotensin system. Cancer Causes Control. 2022;33 (2):313-320. doi: 10.1007/s10552-021-01527-w. PubMed PMID:34921656 PubMed Central PMC8776666.
- Kohtamäki, L, Arjama, M, Mäkelä, S, Ianevski, P, Välimäki, K, Juteau, S et al.. High-throughput ex vivo drug testing identifies potential drugs and drug combinations for NRAS-positive malignant melanoma. Transl Oncol. 2022;15 (1):101290. doi: 10.1016/j.tranon.2021.101290. PubMed PMID:34837846 PubMed Central PMC8633005.
- Ungureanu, D, Țăranu, N, Ghiga, DA, Isopescu, DN, Mihai, P, Cozmanciuc, R et al.. Diagonal Tensile Test on Masonry Panels Strengthened with Textile-Reinforced Mortar. Materials (Basel). 2021;14 (22):. doi: 10.3390/ma14227021. PubMed PMID:34832431 PubMed Central PMC8622034.
- Pöyhönen, A, Åkerla, J, Koskimäki, J, Tammela, TLJ, Auvinen, A. Sauna habits/bathing and changes in lower urinary tract symptoms – Tampere Ageing Male Urologic Study (TAMUS). Scand J Urol. 2022;56 (1):77-82. doi: 10.1080/21681805.2021.2002403. PubMed PMID:34783288 .
- Loukovaara, S, Auvinen, A, Haukka, J. Associations between systemic medications and development of wet age-related macular degeneration. Acta Ophthalmol. 2022;100 (5):572-582. doi: 10.1111/aos.15056. PubMed PMID:34779110 .
- Lupășteanu, V, Ungureanu, D, Țăranu, N, Isopescu, DN, Lupășteanu, R, Mihai, P et al.. Structural Response of Bonded Joints between FRP Composite Strips and Steel Plates. Materials (Basel). 2021;14 (21):. doi: 10.3390/ma14216722. PubMed PMID:34772248 PubMed Central PMC8588173.
- Ventelä, J, Nikkilä, A, Jukkola, A, Lohi, O. Incidence and outcomes of cancer in 16- to 17-year-old adolescents. Acta Paediatr. 2022;111 (2):442-444. doi: 10.1111/apa.16161. PubMed PMID:34689375 PubMed Central PMC9299452.
- Emmert-Streib, F, Manjang, K, Dehmer, M, Yli-Harja, O, Auvinen, A. Are There Limits in Explainability of Prognostic Biomarkers? Scrutinizing Biological Utility of Established Signatures. Cancers (Basel). 2021;13 (20):. doi: 10.3390/cancers13205087. PubMed PMID:34680236 PubMed Central PMC8533990.
- Vöhringer, HS, Sanderson, T, Sinnott, M, De Maio, N, Nguyen, T, Goater, R et al.. Genomic reconstruction of the SARS-CoV-2 epidemic in England. Nature. 2021;600 (7889):506-511. doi: 10.1038/s41586-021-04069-y. PubMed PMID:34649268 PubMed Central PMC8674138.
- Beyer, K, MacLennan, SJ, Moris, L, Lardas, M, Mastris, K, Hooker, G et al.. The Key Role of Patient Involvement in the Development of Core Outcome Sets in Prostate Cancer. Eur Urol Focus. 2021;7 (5):943-946. doi: 10.1016/j.euf.2021.09.008. PubMed PMID:34602368 .
- Li, QK, Chen, J, Hu, Y, Höti, N, Lih, TM, Thomas, SN et al.. Proteomic characterization of primary and metastatic prostate cancer reveals reduced proteinase activity in aggressive tumors. Sci Rep. 2021;11 (1):18936. doi: 10.1038/s41598-021-98410-0. PubMed PMID:34556748 PubMed Central PMC8460832.
- Taavitsainen, S, Engedal, N, Cao, S, Handle, F, Erickson, A, Prekovic, S et al.. Single-cell ATAC and RNA sequencing reveal pre-existing and persistent cells associated with prostate cancer relapse. Nat Commun. 2021;12 (1):5307. doi: 10.1038/s41467-021-25624-1. PubMed PMID:34489465 PubMed Central PMC8421417.
- Barchuk, A, Tursun-Zade, R, Belayev, A, Moore, M, Komarov, Y, Moshina, N et al.. Comparability and validity of cancer registry data in the northwest of Russia. Acta Oncol. 2021;60 (10):1264-1271. doi: 10.1080/0284186X.2021.1967443. PubMed PMID:34424113 .
- Soronen, V, Talala, K, Raitanen, J, Taari, K, Tammela, T, Auvinen, A et al.. Digital rectal examination in prostate cancer screening at PSA level 3.0-3.9 ng/ml: long-term results from a randomized trial. Scand J Urol. 2021;55 (5):348-353. doi: 10.1080/21681805.2021.1966095. PubMed PMID:34409927 .
- van Tilburg, CM, Pfaff, E, Pajtler, KW, Langenberg, KPS, Fiesel, P, Jones, BC et al.. The Pediatric Precision Oncology INFORM Registry: Clinical Outcome and Benefit for Patients with Very High-Evidence Targets. Cancer Discov. 2021;11 (11):2764-2779. doi: 10.1158/2159-8290.CD-21-0094. PubMed PMID:34373263 PubMed Central PMC9414287.
- Jacome Sanz, D, Raivola, J, Karvonen, H, Arjama, M, Barker, H, Murumägi, A et al.. Evaluating Targeted Therapies in Ovarian Cancer Metabolism: Novel Role for PCSK9 and Second Generation mTOR Inhibitors. Cancers (Basel). 2021;13 (15):. doi: 10.3390/cancers13153727. PubMed PMID:34359627 PubMed Central PMC8345177.
- Ketola, K, Kaljunen, H, Taavitsainen, S, Kaarijärvi, R, Järvelä, E, Rodríguez-Martín, B et al.. Subclone Eradication Analysis Identifies Targets for Enhanced Cancer Therapy and Reveals L1 Retrotransposition as a Dynamic Source of Cancer Heterogeneity. Cancer Res. 2021;81 (19):4901-4909. doi: 10.1158/0008-5472.CAN-21-0371. PubMed PMID:34348967 PubMed Central PMC9397610.
- Jasu, J, Tolonen, T, Antonarakis, ES, Beltran, H, Halabi, S, Eisenberger, MA et al.. Combined Longitudinal Clinical and Autopsy Phenomic Assessment in Lethal Metastatic Prostate Cancer: Recommendations for Advancing Precision Medicine. Eur Urol Open Sci. 2021;30 :47-62. doi: 10.1016/j.euros.2021.05.011. PubMed PMID:34337548 PubMed Central PMC8317817.
- Walter, SD, Hu, J, Talala, K, Tammela, T, Taari, K, Auvinen, A et al.. Estimating the rate of overdiagnosis with prostate cancer screening: evidence from the Finnish component of the European Randomized Study of Screening for Prostate Cancer. Cancer Causes Control. 2021;32 (11):1299-1313. doi: 10.1007/s10552-021-01480-8. PubMed PMID:34313874 .
- Crump, RT, Remmers, S, Van Hemelrijck, M, Helleman, J, Nieboer, D, Roobol, MJ et al.. Using the Movember Foundation’s GAP3 cohort to measure the effect of active surveillance on patient-reported urinary and sexual function-a retrospective study in low-risk prostate cancer patients. Transl Androl Urol. 2021;10 (6):2719-2727. doi: 10.21037/tau-20-1255. PubMed PMID:34295757 PubMed Central PMC8261406.
- Kukkonen, K, Taavitsainen, S, Huhtala, L, Uusi-Makela, J, Granberg, KJ, Nykter, M et al.. Chromatin and Epigenetic Dysregulation of Prostate Cancer Development, Progression, and Therapeutic Response. Cancers (Basel). 2021;13 (13):. doi: 10.3390/cancers13133325. PubMed PMID:34283056 PubMed Central PMC8268970.
- Wollschläger, D, Auvinen, A, Blettner, M, Zeeb, H. Methodological considerations for interrupted time series analysis in radiation epidemiology: an overview. J Radiol Prot. 2021;41 (4):. doi: 10.1088/1361-6498/ac149c. PubMed PMID:34261051 .
- Immonen, E, Nikkilä, A, Peltomäki, T, Aine, L, Lohi, O. Late adverse effects of childhood acute lymphoblastic leukemia treatment on developing dentition. Pediatr Blood Cancer. 2021;68 (9):e29200. doi: 10.1002/pbc.29200. PubMed PMID:34228397 .
- Jacome Sanz, D, Saralahti, AK, Pekkarinen, M, Kesseli, J, Nykter, M, Rämet, M et al.. Proprotein convertase subtilisin/kexin type 9 regulates the production of acute-phase reactants from the liver. Liver Int. 2021;41 (10):2511-2522. doi: 10.1111/liv.14993. PubMed PMID:34174143 .
- Meng, B, Kemp, SA, Papa, G, Datir, R, Ferreira, IATM, Marelli, S et al.. Recurrent emergence of SARS-CoV-2 spike deletion H69/V70 and its role in the Alpha variant B.1.1.7. Cell Rep. 2021;35 (13):109292. doi: 10.1016/j.celrep.2021.109292. PubMed PMID:34166617 PubMed Central PMC8185188.
- Raittinen, PVH, Syvälä, H, Tammela, TLJ, Häkkinen, MR, Ilmonen, P, Auriola, S et al.. Atorvastatin induces adrenal androgen downshift in men with prostate cancer: A post Hoc analysis of a pilot adaptive Randomised clinical trial. EBioMedicine. 2021;68 :103432. doi: 10.1016/j.ebiom.2021.103432. PubMed PMID:34144486 PubMed Central PMC8219992.
- Launonen, KM, Paakinaho, V, Sigismondo, G, Malinen, M, Sironen, R, Hartikainen, JM et al.. Chromatin-directed proteomics-identified network of endogenous androgen receptor in prostate cancer cells. Oncogene. 2021;40 (27):4567-4579. doi: 10.1038/s41388-021-01887-2. PubMed PMID:34127815 PubMed Central PMC8266679.
- Annala, M, Taavitsainen, S, Khalaf, DJ, Vandekerkhove, G, Beja, K, Sipola, J et al.. Evolution of Castration-Resistant Prostate Cancer in ctDNA during Sequential Androgen Receptor Pathway Inhibition. Clin Cancer Res. 2021;27 (16):4610-4623. doi: 10.1158/1078-0432.CCR-21-1625. PubMed PMID:34083234 .
- Mäkinen, A, Nikkilä, A, Mehtonen, J, Teppo, S, Oksa, L, Nordlund, J et al.. Expression of BCL6 in paediatric B-cell acute lymphoblastic leukaemia and association with prognosis. Pathology. 2021;53 (7):875-882. doi: 10.1016/j.pathol.2021.02.013. PubMed PMID:34049715 .
- Sipeky, C, Tammela, TLJ, Auvinen, A, Schleutker, J. Novel prostate cancer susceptibility gene SP6 predisposes patients to aggressive disease. Prostate Cancer Prostatic Dis. 2021;24 (4):1158-1166. doi: 10.1038/s41391-021-00378-5. PubMed PMID:34012061 PubMed Central PMC8616752.
- Filppu, P, Tanjore Ramanathan, J, Granberg, KJ, Gucciardo, E, Haapasalo, H, Lehti, K et al.. CD109-GP130 interaction drives glioblastoma stem cell plasticity and chemoresistance through STAT3 activity. JCI Insight. 2021;6 (9):. doi: 10.1172/jci.insight.141486. PubMed PMID:33986188 PubMed Central PMC8262342.
- Eerola, SK, Kohvakka, A, Tammela, TLJ, Koskinen, PJ, Latonen, L, Visakorpi, T et al.. Expression and ERG regulation of PIM kinases in prostate cancer. Cancer Med. 2021;10 (10):3427-3436. doi: 10.1002/cam4.3893. PubMed PMID:33932111 PubMed Central PMC8124112.
- Rajamäki, K, Taira, A, Katainen, R, Välimäki, N, Kuosmanen, A, Plaketti, RM et al.. Genetic and Epigenetic Characteristics of Inflammatory Bowel Disease-Associated Colorectal Cancer. Gastroenterology. 2021;161 (2):592-607. doi: 10.1053/j.gastro.2021.04.042. PubMed PMID:33930428 .
- Cangiano, M, Grudniewska, M, Salji, MJ, Nykter, M, Jenster, G, Urbanucci, A et al.. Gene Regulation Network Analysis on Human Prostate Orthografts Highlights a Potential Role for the Regulon in Clinical Prostate Cancer. Cancers (Basel). 2021;13 (9):. doi: 10.3390/cancers13092094. PubMed PMID:33925994 PubMed Central PMC8123677.
- Van Hemelrijck, M, Ji, X, Helleman, J, Roobol, MJ, Nieboer, D, Bangma, C et al.. A first step towards a global nomogram to predict disease progression for men on active surveillance. Transl Androl Urol. 2021;10 (3):1102-1109. doi: 10.21037/tau-20-1082. PubMed PMID:33850745 PubMed Central PMC8039580.
- Mäkinen, A, Nikkilä, A, Haapaniemi, T, Oksa, L, Mehtonen, J, Vänskä, M et al.. Associates with Proliferative Phenotype and Prognostic Features in B-Cell Acute Lymphoblastic Leukemia. Cancers (Basel). 2021;13 (7):. doi: 10.3390/cancers13071505. PubMed PMID:33805930 PubMed Central PMC8037952.
- Vettenranta, A, Murtola, TJ, Talala, K, Taari, K, Stenman, UH, Tammela, TLJ et al.. Outcomes of prostate cancer screening among men using antidiabetic medication. Sci Rep. 2021;11 (1):7363. doi: 10.1038/s41598-021-86534-2. PubMed PMID:33795720 PubMed Central PMC8016840.
- Peltomaa, AI, Raittinen, P, Talala, K, Taari, K, Tammela, TLJ, Auvinen, A et al.. Prostate cancer prognosis after initiation of androgen deprivation therapy among statin users. A population-based cohort study. Prostate Cancer Prostatic Dis. 2021;24 (3):917-924. doi: 10.1038/s41391-021-00351-2. PubMed PMID:33790420 PubMed Central PMC8384625.
- Collier, DA, De Marco, A, Ferreira, IATM, Meng, B, Datir, RP, Walls, AC et al.. Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies. Nature. 2021;593 (7857):136-141. doi: 10.1038/s41586-021-03412-7. PubMed PMID:33706364 PubMed Central PMC7616976.
- Vihervuori, VJ, Talala, K, Taari, K, Lahtela, J, Tammela, TLJ, Auvinen, A et al.. Antidiabetic Drugs and Prostate Cancer Prognosis in a Finnish Population-Based Cohort. Cancer Epidemiol Biomarkers Prev. 2021;30 (5):982-989. doi: 10.1158/1055-9965.EPI-19-0580. PubMed PMID:33653815 .
- Salminen, JK, Kuoppamäki, V, Talala, K, Taari, K, Mäkinen, J, Peltola, J et al.. Antiepileptic drugs and prostate cancer risk in the Finnish Randomized Study of Screening for Prostate Cancer. Int J Cancer. 2021;149 (2):307-315. doi: 10.1002/ijc.33535. PubMed PMID:33634851 .
- Bruinsma, SM, Nieboer, D, Roobol, MJ, Bangma, CH, Verbeek, JFM, Gnanapragasam, V et al.. Risk-Based Selection for Active Surveillance: Results of the Movember Foundation’s Global Action Plan Prostate Cancer Active Surveillance (GAP3) Initiative. J Urol. 2021;206 (1):62-68. doi: 10.1097/JU.0000000000001700. PubMed PMID:33617330 .
- Khan, MW, Juutilainen, J, Auvinen, A, Naarala, J, Pukkala, E, Roivainen, P et al.. A cohort study on adult hematological malignancies and brain tumors in relation to magnetic fields from indoor transformer stations. Int J Hyg Environ Health. 2021;233 :113712. doi: 10.1016/j.ijheh.2021.113712. PubMed PMID:33601135 .
- Winter, G, Kirschner-Schwabe, R, Groeneveld-Krentz, S, Escherich, G, Möricke, A, von Stackelberg, A et al.. Clinical and genetic characteristics of children with acute lymphoblastic leukemia and Li-Fraumeni syndrome. Leukemia. 2021;35 (5):1475-1479. doi: 10.1038/s41375-021-01163-y. PubMed PMID:33580201 PubMed Central PMC8102191.
- Beyer, K, Moris, L, Lardas, M, Haire, A, Barletta, F, Scuderi, S et al.. Diagnostic and prognostic factors in patients with prostate cancer: a systematic review protocol. BMJ Open. 2021;11 (2):e040531. doi: 10.1136/bmjopen-2020-040531. PubMed PMID:33574142 PubMed Central PMC7880102.
- Siltari, A, Auvinen, A, Murtola, TJ. Pharmacoepidemiological Evaluation in Prostate Cancer-Common Pitfalls and How to Avoid Them. Cancers (Basel). 2021;13 (4):. doi: 10.3390/cancers13040696. PubMed PMID:33572236 PubMed Central PMC7914977.
- Lange, J, Remmers, S, Gulati, R, Bill-Axelson, A, Johansson, JE, Kwiatkowski, M et al.. Impact of cancer screening on metastasis: A prostate cancer case study. J Med Screen. 2021;28 (4):480-487. doi: 10.1177/0969141321989738. PubMed PMID:33563084 PubMed Central PMC8349931.
- Kemp, SA, Collier, DA, Datir, RP, Ferreira, IATM, Gayed, S, Jahun, A et al.. SARS-CoV-2 evolution during treatment of chronic infection. Nature. 2021;592 (7853):277-282. doi: 10.1038/s41586-021-03291-y. PubMed PMID:33545711 PubMed Central PMC7610568.
- Murumägi, A, Ungureanu, D, Arjama, M, Bützow, R, Lohi, J, Sariola, H et al.. STRN-ALK rearranged pediatric malignant peritoneal mesothelioma – Functional testing of 527 cancer drugs in patient-derived cancer cells. Transl Oncol. 2021;14 (4):101027. doi: 10.1016/j.tranon.2021.101027. PubMed PMID:33530027 PubMed Central PMC7851186.
- Neupane, S, Nevalainen, J, Raitanen, J, Talala, K, Kujala, P, Taari, K et al.. Prognostic Index for Predicting Prostate Cancer Survival in a Randomized Screening Trial: Development and Validation. Cancers (Basel). 2021;13 (3):. doi: 10.3390/cancers13030435. PubMed PMID:33498854 PubMed Central PMC7865328.
- Conti, DV, Darst, BF, Moss, LC, Saunders, EJ, Sheng, X, Chou, A et al.. Publisher Correction: Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction. Nat Genet. 2021;53 (3):413. doi: 10.1038/s41588-021-00786-2. PubMed PMID:33473200 .
- Cerqueira, JXM, Saavalainen, P, Kurppa, K, Laurikka, P, Huhtala, H, Nykter, M et al.. Independent and cumulative coeliac disease-susceptibility loci are associated with distinct disease phenotypes. J Hum Genet. 2021;66 (6):613-623. doi: 10.1038/s10038-020-00888-5. PubMed PMID:33446885 PubMed Central PMC8144013.
- Karlsson, Q, Brook, MN, Dadaev, T, Wakerell, S, Saunders, EJ, Muir, K et al.. Rare Germline Variants in ATM Predispose to Prostate Cancer: A PRACTICAL Consortium Study. Eur Urol Oncol. 2021;4 (4):570-579. doi: 10.1016/j.euo.2020.12.001. PubMed PMID:33436325 PubMed Central PMC8381233.
- Alanko, J, Tanner, M, Vanninen, R, Auvinen, A, Isola, J. Triple-negative and HER2-positive breast cancers found by mammography screening show excellent prognosis. Breast Cancer Res Treat. 2021;187 (1):267-274. doi: 10.1007/s10549-020-06060-z. PubMed PMID:33420595 PubMed Central PMC8062374.
- Vandekerkhove, G, Lavoie, JM, Annala, M, Murtha, AJ, Sundahl, N, Walz, S et al.. Plasma ctDNA is a tumor tissue surrogate and enables clinical-genomic stratification of metastatic bladder cancer. Nat Commun. 2021;12 (1):184. doi: 10.1038/s41467-020-20493-6. PubMed PMID:33420073 PubMed Central PMC7794518.
- Conti, DV, Darst, BF, Moss, LC, Saunders, EJ, Sheng, X, Chou, A et al.. Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction. Nat Genet. 2021;53 (1):65-75. doi: 10.1038/s41588-020-00748-0. PubMed PMID:33398198 PubMed Central PMC8148035.
- Valkonen, M, Hognas, G, Bova, GS, Ruusuvuori, P. Generalized Fixation Invariant Nuclei Detection Through Domain Adaptation Based Deep Learning. IEEE J Biomed Health Inform. 2021;25 (5):1747-1757. doi: 10.1109/JBHI.2020.3039414. PubMed PMID:33211668 .
- Pakarainen, T, Nevalainen, J, Talala, K, Taari, K, Raitanen, J, Kujala, P et al.. Number of screening rounds attended and incidence of high-risk prostate cancer in the Finnish Randomized Study of Screening for Prostate Cancer (FinRSPC). Cancer. 2021;127 (2):188-192. doi: 10.1002/cncr.33254. PubMed PMID:33048394 .
- Pöyhönen, A, Åkerla, J, Koskimäki, J, Tammela, TLJ, Auvinen, A. Seasonal changes in occurrence and severity of lower urinary tract symptoms-Tampere Aging Male Urologic Study (TAMUS). Low Urin Tract Symptoms. 2021;13 (2):216-223. doi: 10.1111/luts.12353. PubMed PMID:33034153 .
- Tomer, A, Nieboer, D, Roobol, MJ, Bjartell, A, Steyerberg, EW, Rizopoulos, D et al.. Personalised biopsy schedules based on risk of Gleason upgrading for patients with low-risk prostate cancer on active surveillance. BJU Int. 2021;127 (1):96-107. doi: 10.1111/bju.15136. PubMed PMID:32531869 PubMed Central PMC7818468.
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